Yersinia Infection in Acute Appendicitis in Children in Shebin Elkom Teaching Hospital

Achoimre

Background: Yersinia enterocolotica is being recognized as an important bacterial cause of acute gastrointestinal infection. The association of yersinia entrocolotica infections with acute appendicitis has been suggested (Tae Joon Son et. al, 2009). The aim to ascertain whether yersinia entrocolotica is a possible infectious agent in appendicitis in Shebin Elkom. We try to support or to deny this suggestion. Methods: A prospective randomized study was done to 48 patients admitted to surgical department from outpatient clinic of Shebin Elkom Teaching Hospital over 14 months from January 2020 to March 2021The purpose and nature of the study were explained to all participants and written voluntary consents were obtained before their participation. Approval was taken from the research committee of the General Organization of Teaching Hospitals and Institutions (GOTHI) with approval number HSH00039. Our patient ages ranged from 2.5 years to 15 years old (mean7.04 ± 1.93).26 were males and 22 were females. All of them were diagnosed clinically as having acute appendicitis. The study included two groups classified as follows: Group I: 39 patients (positive histopathology of appendicitis and group II: 9 patients (negative histopathology of appendicitis). Appendectomy was done for all patients, followed by histopathological examination and appendix culture on Yersinia selective mediaYersinia Selective Agar Base Results: The results showed that from the 48 patients, 39 were positive histopathology of appendicitis (the specimens were inflamed appendices) group (1). The rest of patients were negative histopathology of appendicitis (normal appendices) group (2). In group (1): 10 patients of the 39 were +ve for Yersinia with 25.6% and 29 patients were -ve 74.4%. In group (2): all the nine patients were -ve for Yersinia infection with100%. We compared between the two groups using the test of significance (chi square test). It was 2.92. The p value was 0.17, it was statistically non-significant. Conclusion: We were unable to implicate Y. enterocolitica as one of the causative pathogens in acute appendicitis However, we thought there to be more need for investigation for association of Y. enterocolitica with acute appendicitis . Physicians should keep recent Y. enterocolitica infection in mind in patients with symptoms resembling appendicitis